This article focused differences on intercultural communication from Korean managers and Vietnamese employees. The objective of this article is to identify disparities and commonalities in business communication practices between Korean managers and Vietnamese employees. The theoretical part of this article is titled as intercultural communication. The definition of intercultural communication, culture’s influence on perception, obstacles in intercultural communication and intercultural communication competences are covered in this part. For empirical research part, qualitative research is used to study the in-depth of this article’s objective. Data was collected through interviews and previous published literatures. The interviews were conducted with six Korean managers, who had extensive of experiences in dealing with people from different cultures. Also, ten Vietnamese employees with experiences in working at Korean FDI in Vietnam for the interview. According to the research results, there were differences as well as similarities perspective on intercultural communication between Korean managers and Vietnamese employees. The research also revealed the challenges experienced by individuals from both cultures when collaborating, encompassing variations in working styles, language proficiency levels, and the use of non-verbal communication. These challenges could create miscommunication and misinterpretation in intercultural communication from the interviewees’ perspective. The research’s findings also addressed strategies for surmounting these challenges. Successful intercultural communication necessitated the cultivation of patience and keen observational skills. Embracing cultural differences while actively seeking common ground provided a foundational understanding for effective communication. Moreover, observations underscored the importance of adaptability, emphasizing the need to tailor communication and behavior to specific contexts. Striving for clarity in communication emerged as a key tactic to prevent misunderstandings.